The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9783599 B1

PDF
Full Text
Expired
Date of Patent:
Oct. 10, 2017

Filed:

Mar. 14, 2014
Applicant:

Patrys Limited, Melbourne, Victoria, AU;

Inventors:

Heinz Peter Vollmers, Wurzburg, DE;

Stephanie Ute Brandlein, Zellingen, DE;

Andreas Thalheimer, Wurzburg, DE;

Leodevico L. Ilag, Balwyn, AU;

Barbara E. Power, Blackburn, AU;

Lishanthi Udabage, Rowville, AU;

Frank Hensel, Wurzburg, DE;

Frank Schoenen, Wurzburg, DE;

Arndt-Rene Kelter, Alfter, DE;

Christopher Garth Hosking, Nunawading, AU;

Assignee:

Patrys Limited, Melbourne, AU;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/395 (2006.01); C07K 16/28 (2006.01); C07K 16/18 (2006.01); A61K 41/00 (2006.01); A61K 51/10 (2006.01); C07K 14/47 (2006.01); C07K 16/30 (2006.01); C12N 15/113 (2010.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61K 41/0095 (2013.01); A61K 51/1045 (2013.01); C07K 14/47 (2013.01); C07K 16/30 (2013.01); C07K 16/3023 (2013.01); C12N 15/113 (2013.01); G01N 33/574 (2013.01); A61K 2039/505 (2013.01); C07K 2317/52 (2013.01); C07K 2317/73 (2013.01); C12N 2310/11 (2013.01); C12N 2310/14 (2013.01);
Abstract

The invention provides LM-1 antibodies, functional fragments, modified and variant forms, nucleic acid and other compositions. The invention also provides antibodies, functional fragments, modified and variant forms that bind to LM-1 antigen (e.g., NONO/nmt55). Antibodies, functional fragments, modified and variant forms, nucleic acid and other compositions are useful in treatment and diagnostic methods. One method includes treating metastasis of a neoplasia, tumor or cancer in a subject in need of treatment by administering to the subject an amount of a LM-1 antibody, an antibody that binds to LM-1 antigen, or a functional fragment thereof, effective to treat metastasis of the neoplasia, tumor or cancer in the subject.


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