The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 10, 2017
Filed:
Jul. 24, 2015
Applicant:
Indiana University Research and Technology Corporation, Indianapolis, IN (US);
Inventors:
Richard D. DiMarchi, Carmel, IN (US);
Bin Yang, Bloomington, IN (US);
Brian Finan, Bloomington, IN (US);
Assignee:
Indiana University Research and Technology Corporation, Indianapolis, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/605 (2006.01); A61K 38/26 (2006.01); C07K 14/72 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
C07K 14/721 (2013.01); A61K 38/26 (2013.01); A61K 47/481 (2013.01); A61K 47/48123 (2013.01); A61K 47/48246 (2013.01); C07K 14/605 (2013.01); C07K 14/72 (2013.01);
Abstract
Provided herein are glucagon superfamily peptides conjugated with NHR ligands that are capable of acting at a nuclear hormone receptor. Also provided herein are pharmaceutical compositions and kits of the conjugates of the invention. Further provided herein are methods of treating a disease, e.g., a metabolic disorder, such as diabetes and obesity, comprising administering the conjugates of the invention.