The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 10, 2017
Filed:
Mar. 11, 2014
Applicant:
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Washington, DC (US);
Inventors:
Louis M. Staudt, Bethesda, MD (US);
Yibin Yang, Rockville, MD (US);
Federico Bernal, Gaithersburg, MD (US);
Amanda L. Whiting, Frederick, MD (US);
Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); G01N 33/574 (2006.01); C12Q 1/68 (2006.01); A61K 38/00 (2006.01); C12N 9/00 (2006.01); A61K 38/17 (2006.01); A61K 45/06 (2006.01); A61N 5/10 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4703 (2013.01); A61K 38/00 (2013.01); A61K 38/1709 (2013.01); A61K 45/06 (2013.01); A61N 5/10 (2013.01); C07K 14/4713 (2013.01); C12N 9/93 (2013.01); C12Q 1/68 (2013.01); C12Y 304/19012 (2013.01); G01N 33/57407 (2013.01);
Abstract
The invention relates to peptide inhibitors of linear ubiquitin chain assembly complex (LUBAC) and to methods of treating diseases including activated B-cell like diffuse large B cell lymphoma (ABC DLBCL) and autoimmune or inflammatory disorders.