The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 10, 2017
Filed:
Dec. 08, 2014
Pottayil Govindan Nair Sasikumar, Bangalore, IN;
Muralidhara Ramachandra, Bangalore, IN;
Suresh Kumar Vadlamani, Bangalore, IN;
Koteswara Rao Vemula, Bangalore, IN;
Leena Khare Satyam, Bangalore, IN;
Krishnaprasad Subbarao, Bangalore, IN;
K. Rajeev Shrimali, Hyderabad, IN;
Sreenivas Kandepu, Hyderabad, IN;
Pottayil Govindan Nair Sasikumar, Bangalore, IN;
Muralidhara Ramachandra, Bangalore, IN;
Suresh Kumar Vadlamani, Bangalore, IN;
Koteswara Rao Vemula, Bangalore, IN;
Leena Khare Satyam, Bangalore, IN;
Krishnaprasad Subbarao, Bangalore, IN;
K. Rajeev Shrimali, Hyderabad, IN;
Sreenivas Kandepu, Hyderabad, IN;
AURIGENE DISCOVERY TECHNOLOGIES LIMITED, Bangalore, IN;
Abstract
The present invention provides immunosuppression compounds to inhibit the programmed cell death 1 (PD1) signalling pathway. The present invention further provides peptide based compositions for treatment of cancer or treatment of infections via immunopotentiation caused by inhibition of immunosuppressive signaling induced by PD-1, PD-L1, or PD-L2 and therapies using them, immunopotentiative substrates included as the active ingredient. Further, the invention provides an application of the compositions containing the peptide moieties for preventive and/or therapeutic agents for cancer, cancer metastasis, immunodeficiency, an infectious disease or the like and an application of peptide moieties as a testing or diagnostic agent or a research agent for such a disease.