The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 10, 2017

Filed:

Sep. 15, 2015
Applicant:

Abbvie Inc., North Chicago, IL (US);

Inventors:

Jerome F. Daanen, Racine, WI (US);

David A. DeGoey, Salem, WI (US);

Jennifer M. Frost, Gurnee, IL (US);

John R. Koenig, Chicago, IL (US);

Steve Latshaw, Elijay, GA (US);

Mark Matulenko, Libertyville, IL (US);

Marc Scanio, Libertyville, IL (US);

Lei Shi, Vernon Hills, CN;

William H. Bunnelle, Mundelein, IL (US);

Assignee:

AbbVie Inc., North Chicago, IL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/497 (2006.01); A61K 31/4178 (2006.01); A61K 31/4985 (2006.01); C07D 403/04 (2006.01); C07D 403/14 (2006.01); C07D 487/14 (2006.01); C07D 491/08 (2006.01); C07D 413/14 (2006.01); C07D 405/14 (2006.01); C07D 417/14 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
C07D 403/14 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 487/14 (2013.01); C07D 491/08 (2013.01);
Abstract

Compounds of formula (I) and pharmaceutically acceptable salts, esters, amides, or radiolabelled forms thereof, wherein A, Rand Rare as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by voltage-gated sodium channels, e.g., Na1.7 and/or Na1.8. Methods for making the compounds are disclosed. Also disclosed are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.


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