The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 10, 2017

Filed:

Jan. 15, 2013
Applicant:

Omeros Corporation, Seattle, WA (US);

Inventors:

Neil S. Cutshall, Snohomish, WA (US);

Jennifer Lynn Gage, Kenmore, WA (US);

Thomas Neil Wheeler, Raleigh, NC (US);

Assignee:

Omeros Corporation, Seattle, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/15 (2006.01); A61P 25/18 (2006.01); A61P 25/16 (2006.01); A61P 25/28 (2006.01); A61P 25/14 (2006.01); C07D 401/04 (2006.01); A61K 31/357 (2006.01); A61K 31/36 (2006.01); A61K 31/40 (2006.01); A61K 31/41 (2006.01); A61K 31/415 (2006.01); A61K 31/4184 (2006.01); A61K 31/4196 (2006.01); A61K 31/425 (2006.01); A61K 31/47 (2006.01); A61K 31/5375 (2006.01); A61K 31/54 (2006.01); C07C 251/86 (2006.01); C07C 251/88 (2006.01); C07C 255/66 (2006.01); C07D 213/56 (2006.01); C07D 213/74 (2006.01); C07D 215/14 (2006.01); C07D 231/12 (2006.01); C07D 235/16 (2006.01); C07D 249/04 (2006.01); C07D 249/08 (2006.01); C07D 257/06 (2006.01); C07D 265/36 (2006.01); C07D 275/02 (2006.01); C07D 295/155 (2006.01); C07D 317/62 (2006.01); C07D 319/18 (2006.01); C07D 333/60 (2006.01); C07C 243/32 (2006.01); C07C 251/80 (2006.01); C07D 295/135 (2006.01);
U.S. Cl.
CPC ...
C07D 401/04 (2013.01); A61K 31/15 (2013.01); A61K 31/357 (2013.01); A61K 31/36 (2013.01); A61K 31/40 (2013.01); A61K 31/41 (2013.01); A61K 31/415 (2013.01); A61K 31/4184 (2013.01); A61K 31/4196 (2013.01); A61K 31/425 (2013.01); A61K 31/47 (2013.01); A61K 31/5375 (2013.01); A61K 31/54 (2013.01); C07C 243/32 (2013.01); C07C 251/80 (2013.01); C07C 251/86 (2013.01); C07C 251/88 (2013.01); C07C 255/66 (2013.01); C07D 213/56 (2013.01); C07D 213/74 (2013.01); C07D 215/14 (2013.01); C07D 231/12 (2013.01); C07D 235/16 (2013.01); C07D 249/04 (2013.01); C07D 249/08 (2013.01); C07D 257/06 (2013.01); C07D 265/36 (2013.01); C07D 275/02 (2013.01); C07D 295/135 (2013.01); C07D 295/155 (2013.01); C07D 317/62 (2013.01); C07D 319/18 (2013.01); C07D 333/60 (2013.01); C07C 2601/08 (2017.05);
Abstract

Compounds that inhibit PDE10 are disclosed that have utility in the treatment of a variety of conditions, including (but not limited to) psychotic, anxiety, movement disorders and/or neurological disorders such as Parkinson's disease, Huntington's disease, Alzheimer's disease, encephalitis, phobias, epilepsy, aphasia, Bell's palsy, cerebral palsy, sleep disorders, pain, Tourette's syndrome, schizophrenia, delusional disorders, drug-induced psychosis and panic and obsessive-compulsive disorders. Pharmaceutically acceptable salts, stereoisomers, solvates and prodrugs of the compounds are also provided. Also disclosed are compositions containing a compound in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for inhibiting PDE10 in a warm-blooded animal in need of the same.


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