The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 10, 2017
Filed:
Mar. 12, 2015
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD (US);
Clifton Dalgard, Chevy Chase, MD (US);
Ahmed Mohamed, Germantown, MD (US);
Meera Srivastava, Potomac, MD (US);
Shiv Srivastava, Potomac, MD (US);
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD (US);
Abstract
Alterations to the ERG gene are some of the most prominent genomic changes associated with many cancers including prostate cancer. Such cancer specific alterations result in the overexpression of wild type ERG protein or an altered ERG protein. The present invention provides selective inhibitors of wild type or an altered ERG protein expression. The ERG inhibitors of the invention, therefore, are therapeutic agents for treating ERG positive cancers.