The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2017
Filed:
Mar. 12, 2014
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Benjamin M. Jackson, Wynnewood, PA (US);
Robert C. Gorman, Lower Gwynedd, PA (US);
Joseph H. Gorman, Lower Gwynedd, PA (US);
Alison M. Pouch, Philadelphia, PA (US);
Chandra M. Sehgal, Wayne, PA (US);
Paul A. Yushkevich, Wynnewood, PA (US);
Brian B. Avants, Philadelphia, PA (US);
Hongzhi Wang, Boiling Springs, PA (US);
The Trustees Of The University Of Pennsylvania, Philadelphia, PA (US);
Abstract
A method is provided for measuring or estimating stress distributions on heart valve leaflets by obtaining three-dimensional images of the heart valve leaflets, segmenting the heart valve leaflets in the three-dimensional images by capturing locally varying thicknesses of the heart valve leaflets in three-dimensional image data to generate an image-derived patient-specific model of the heart valve leaflets, and applying the image-derived patient-specific model of the heart valve leaflets to a finite element analysis (FEA) algorithm to estimate stresses on the heart valve leaflets. The images of the heart valve leaflets may be obtained using real-time 3D transesophageal echocardiography (rt-3DTEE). Volumetric images of the mitral valve at mid-systole may be analyzed by user-initialized segmentation and 3D deformable modeling with continuous medial representation to obtain, a compact representation of shape. The regional leaflet stress distributions may be predicted in normal and diseased (regurgitant) mitral valves using the techniques of the invention.