The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2017
Filed:
May. 16, 2011
Karsten Weber, Leverkusen, DE;
Inke Sabine Feder, Leverkusen, DE;
Karsten Weber, Leverkusen, DE;
Inke Sabine Feder, Leverkusen, DE;
Siemens Healthcare Diagnostics Inc., Tarrytown, NY (US);
Abstract
The invention describes how to estimate delta-Cq values from measured (raw-)Cq values gained from PCR measurements and how to calculate confidence intervals for them. This is realized by the following processing steps: A noise model, which might be constructed on some training PCR data, calculates the distribution of the true target material concentration of a single well for an observed measurement results. Said distribution is calculated for all types of measurement results including 'Numeric' raw-Cq values as well as Cq being 'Undetected', which denotes that no fluorescence signal was detected during all cycles and thus corresponds to no or very few target molecules.