The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2017
Filed:
Aug. 25, 2011
Stephen Yue, Eugene, OR (US);
Gene Shen, Santa Clara, CA (US);
Louis Brogley, Santa Cruz, CA (US);
Lubomir Sebo, Redwood City, CA (US);
Jeffrey Wegener, Cupertino, CA (US);
Stephen Yue, Eugene, OR (US);
Gene Shen, Santa Clara, CA (US);
Louis Brogley, Santa Cruz, CA (US);
Lubomir Sebo, Redwood City, CA (US);
Jeffrey Wegener, Cupertino, CA (US);
Pacific Biosciences of California, Inc., Menlo Park, CA (US);
Abstract
In various embodiments, the present invention provides fluorescent dyes that are linked to another species through an adaptor moiety. In an exemplary embodiment, the dye is linked to a polyphosphate nucleic acid through an adaptor. An adaptor can be a component of a linker. These conjugates find use in single molecule DNA sequencing and other applications. In various embodiments, the dye moiety is a cyanine dye. Cyanine dyes that are highly charged, such as those including multiple sulfonate, alkylsulfonate, carboxylate and/or alkylcarboxylate moieties are examples of cyanine dyes of use in the compounds of the invention.