The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2017
Filed:
Mar. 14, 2013
Applicants:
Baxalta Gmbh, Glattpark (Opfikon), CH;
Baxalta Incorporated, Bannockburn, IL (US);
Inventors:
Michael Dockal, Vienna, AT;
Hartmut Ehrlich, Vienna, AT;
Friedrich Scheiflinger, Vienna, AT;
Ulf Reimer, Berlin, DE;
Ulrich Reineke, Berlin, DE;
Thomas Polakowski, Berlin, DE;
Eberhard Schneider, Denkte, DE;
Assignees:
Baxalta GmbH, Glattpark (Opfikon), CH;
Baxalta Incorporated, Bannockburn, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); A61K 47/48 (2006.01); C07K 7/08 (2006.01); C07K 14/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4703 (2013.01); A61K 47/48146 (2013.01); A61K 47/48215 (2013.01); C07K 7/08 (2013.01); C07K 14/001 (2013.01); A61K 38/00 (2013.01);
Abstract
The invention provides peptides that bind Tissue Factor Pathway Inhibitor (TFPI), including TFPI-inhibitory peptides, and compositions thereof. The peptides may be used to inhibit a TFPI, enhance thrombin formation in a clotting factor-deficient subject, increase blood clot formation in a subject, and/or treat a blood coagulation disorder in a subject.