The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2017
Filed:
Mar. 04, 2016
Applicant:
Mallinckrodt Llc, Hazelwood, MO (US);
Inventors:
Dennis A. Moore, Ferguson, MO (US);
Raghavan Rajagopalan, St. Peters, MO (US);
Assignee:
GUERBET, Villepinte, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 5/00 (2006.01); C07D 257/02 (2006.01); C07D 295/15 (2006.01);
U.S. Cl.
CPC ...
C07F 5/003 (2013.01); C07D 257/02 (2013.01); C07D 295/15 (2013.01);
Abstract
The present disclosure relates generally to a process for the synthesis of 1,4,7,10-tetraazacyclododecane ligands, chelates, and derivatives thereof. In particular, the present disclosure is directed to a process for the synthesis of 1,4,7,10-tetraaza-1,4,7,10-tetrakis(carboxymethyl)cyclododecane (DOTA) ligands, corresponding DOTA-metal chelates, and various derivatives thereof.