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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9776979 B1

PDFFull Text
Date of Patent:
Oct. 03, 2017

Filed:

Sep. 26, 2014

Ebi2 modulators

Applicant:

Sanford-burnham Medical Research Institute, La Jolla, CA (US);

Inventors:

Anthony B. Pinkerton, San Diego, CA (US);

Robert Ardecky, La Jolla, CA (US);

Eduard A. Sergienko, San Diego, CA (US);

Marcos Gonzalez-Lopez, La Jolla, CA (US);

Santhi Reddy Ganji, La Jolla, CA (US);

Jiwen Zou, San Diego, CA (US);

Assignee:

SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE, La Jolla, CA (US);

Attorney:

Wilson Sonsini Goodrich & Rosati

Primary Examiner:

Erich A Leeser

Int. Cl.
CPC ...
C07D 295/16 (2006.01); C07D 471/04 (2006.01); C07D 471/10 (2006.01); C07F 5/02 (2006.01); C07D 209/12 (2006.01); C07D 211/26 (2006.01); C07D 215/14 (2006.01); C07D 235/10 (2006.01); C07D 257/04 (2006.01); C07D 295/26 (2006.01); C07D 317/46 (2006.01); C07D 333/56 (2006.01); C07D 401/06 (2006.01); C07D 403/12 (2006.01); C07D 495/04 (2006.01); C07F 9/6509 (2006.01);
U.S. Cl.
CPC ...
C07D 295/16 (2013.01); C07D 209/12 (2013.01); C07D 211/26 (2013.01); C07D 215/14 (2013.01); C07D 235/10 (2013.01); C07D 257/04 (2013.01); C07D 295/26 (2013.01); C07D 317/46 (2013.01); C07D 333/56 (2013.01); C07D 401/06 (2013.01); C07D 403/12 (2013.01); C07D 471/04 (2013.01); C07D 471/10 (2013.01); C07D 495/04 (2013.01); C07F 5/025 (2013.01); C07F 9/650958 (2013.01);
Abstract

Provided herein are small molecule Epstein-Barr virus-induced G-protein coupled receptor 2 (EBI2) modulator compounds, compositions comprising the compounds, and methods of using the compounds and compositions comprising the compounds. EBI2 is a therapeutic target for the treatment of a variety of diseases or conditions. In some embodiments, EBI2 is a therapeutic target for the treatment of diseases or conditions such as, but not limited to, autoimmune diseases or conditions, cancer, and cardiovascular disease.

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