The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2017
Filed:
Dec. 21, 2016
Applicant:
Zhejiang Hisun Pharmaceutical Co., Ltd., Taizhou, CN;
Inventors:
Hongyuan Wei, Tianjin, CN;
Chongjun Liu, Tianjin, CN;
Xuyang Zhao, Chengdu, CN;
Xiaojie Xu, Taizhou, CN;
Hua Bai, Taizhou, CN;
Yuncai Zhang, Taizhou, CN;
Assignee:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 205/08 (2006.01); A61K 31/397 (2006.01);
U.S. Cl.
CPC ...
C07D 205/08 (2013.01); A61K 31/397 (2013.01); C07B 2200/13 (2013.01);
Abstract
The present invention provides crystal forms of the compound of (3R,4S)-4-(4-hydroxyphenyl)-3-[3-(4-fluorophenyl)-4-hydroxybut-2(Z)-enyl]-1-(4-fluorophenyl)-2-azetidinone (formula A). The crystal forms can be characterized by X-ray powder diffraction (XRPD) spectra, differential scanning calorimetry (DSC) spectra, infrared absorption spectra and so on. Meanwhile, the present invention also provides methods for preparing the crystal forms of the compound of formula A, pharmaceutical compositions and uses thereof.