The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 03, 2017

Filed:

Feb. 02, 2016
Applicant:

Molecular Partners Ag, Schlieren, CH;

Inventors:

Daniel Steiner, Zürich, CH;

Hans Kaspar Binz, Birmensdorf, CH;

Maya Gulotti-Georgieva, Wettswil a.A., CH;

Frieder W. Merz, Mellingen, CH;

Douglas Phillips, Baden, CH;

Ivo Sonderegger, Urdorf, CH;

Assignee:

Molecular Partners AG, Schlieren, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/48 (2006.01); C07K 14/47 (2006.01); C07K 14/00 (2006.01); C07K 16/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48246 (2013.01); C07K 14/001 (2013.01); C07K 14/47 (2013.01); C07K 14/4702 (2013.01); C07K 16/00 (2013.01); A61K 38/00 (2013.01); C07K 2318/20 (2013.01); C07K 2319/00 (2013.01); C07K 2319/21 (2013.01); C07K 2319/22 (2013.01); C07K 2319/30 (2013.01); C07K 2319/31 (2013.01); C07K 2319/55 (2013.01); C07K 2319/60 (2013.01);
Abstract

New designed repeat proteins with binding specificity for serum albumin are described, as well as nucleic acids encoding such serum albumin binding proteins, pharmaceutical compositions comprising such proteins, the use of such proteins to modify the pharmacokinetics of therapeutic relevant polypeptides and the use of such proteins in the treatment of diseases. The repeat proteins of the invention have a substantially increased half-life in plasma compared to proteins not binding serum albumin.


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