The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9772336 B1

PDF
Full Text
Expired
Date of Patent:
Sep. 26, 2017

Filed:

Sep. 16, 2015
Applicant:

National Center for Biological Sciences, Bangalore, IN;

Inventors:

Yamuna Krishnan, Bangalore, IN;

Saikat Chakraborty, Bangalore, IN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C07H 21/00 (2006.01); G01N 33/84 (2006.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
G01N 33/84 (2013.01); C12Q 1/68 (2013.01); G01N 21/6428 (2013.01); G01N 2021/6432 (2013.01); G01N 2021/6441 (2013.01); Y10T 436/143333 (2015.01);
Abstract

Disclosed are nucleic acid-based molecular switches that respond to changes in pH. The switches may be used in DNA nanodevices. The switches may also act as sensors for measuring the pH of a sample, including cells, regions thereof, and whole organisms. The switch includes an A-motif that forms at acidic pH. Also disclosed are compositions and methods for measuring the pH of cells or regions thereof, such as vesicles, the nucleus, mitochondrial matrix, or the Golgi lumen.


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Krishnan, Yamuna. (2017). Method for determining agent capacity to alter ph using poly da nucleic acid switches (U.S. Patent No. 9772336). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9772336

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