The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 26, 2017

Filed:

Mar. 14, 2014
Applicant:

Beckman Coulter, Inc., Brea, CA (US);

Inventors:

Marshall Donnie Graham, Nicholasville, KY (US);

William Gerry Graham, Nicholasville, KY (US);

James P. Clarkin, Scottsdale, AZ (US);

Mark A. Wells, Davie, FL (US);

Jose M. Cano, Miami, FL (US);

Carlos Alberto Arboleda, Miami, FL (US);

Armando J. Sanchez, Miami, FL (US);

Assignee:

Beckman Coulter, Inc., Brea, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 21/05 (2006.01); C03B 23/047 (2006.01); C03C 27/00 (2006.01); G01N 15/14 (2006.01); G01N 15/10 (2006.01);
U.S. Cl.
CPC ...
G01N 21/05 (2013.01); C03B 23/047 (2013.01); C03C 27/00 (2013.01); G01N 15/1434 (2013.01); G01N 2015/1006 (2013.01); G01N 2015/149 (2013.01); G01N 2015/1452 (2013.01); G01N 2015/1486 (2013.01); G01N 2201/02 (2013.01); Y02P 40/57 (2015.11);
Abstract

An improved optical flow cell adapted for use in a flow cytometer for differentiating formed bodies (e.g., blood cells) in liquid suspensions. Preferably manufactured by assembling, aligning, and optically joining at least two elements made from transparent material, the improved flow cell has a seamless internal flow channel of preferably non-circular cross-section in a cylindrical first element through which prepared samples can be metered and an independent second element having an external envelope suited to acquisition of optical parameters from formed bodies in such suspensions, the second element being conforming and alignable to the first element so that non-axisymmetric refractive effects on optical characterizing parameters of formed bodies passing through the flow channel in the first element may be minimized before the two elements are optically joined and fixed in working spatial relationship.


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