The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 26, 2017

Filed:

Oct. 03, 2013
Applicants:

Zymeworks Inc., Vancouver, CA;

National Research Council of Canada, Ottawa, CA;

Inventors:

Anders Ohrn, Toronto, CA;

Adam Louis Corper, Vancouver, CA;

Gordon Yiu Kon Ng, Vancouver, CA;

Antonios Samiotakis, New Westminster, CA;

Yang-Chieh Chou, Vancouver, CA;

Jason Baardsnes, Montreal, CA;

Maureen O'Connor-McCourt, Beaconsfield, CA;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); C12N 15/10 (2006.01); A61K 39/00 (2006.01); C07K 16/46 (2006.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1055 (2013.01); A61K 39/00 (2013.01); C07K 16/468 (2013.01); G01N 21/6486 (2013.01); C07K 2317/55 (2013.01);
Abstract

Provided is a method of quantitatively determining the ability of individual IgG heavy chains to selectively pair with a particular IgG light chain when the heavy chains and two unique light chains are co-expressed. The method provides results with reasonable throughput and is robust and accurate. The co-expressed heavy and light chains do not need to be isolated and purified which enables more efficient screening.


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