The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 26, 2017

Filed:

Mar. 20, 2015
Applicant:

Bristol-myers Squibb Company, Princeton, NJ (US);

Inventors:

Stuart Emanuel, Doylestown, PA (US);

Linda Engle, Framingham, MA (US);

Ray Camphausen, Wayland, MA (US);

Martin C. Wright, Belmont, MA (US);

Ginger Chao Rakestraw, Cambridge, MA (US);

Marco Gottardis, Princeton, NJ (US);

Joan Carboni, Yardley, PA (US);

Assignee:

BRISTOL-MYERS SQUIBB COMPANY, Princeton, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); A61K 38/39 (2006.01); C07K 14/435 (2006.01); C07K 14/475 (2006.01); C07K 14/78 (2006.01); C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); C07K 14/705 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/78 (2013.01); A61K 38/39 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); C07K 14/475 (2013.01); C07K 16/2863 (2013.01); A61K 2039/505 (2013.01); C07K 2317/31 (2013.01); C07K 2317/34 (2013.01); C07K 2317/92 (2013.01); C07K 2318/20 (2013.01); C07K 2319/30 (2013.01);
Abstract

The present invention relates to bispecific molecules comprising an EGFR binding domain and a distinct IGFIR binding domain for use in diagnostic, research and therapeutic applications. The invention further relates to cells comprising such proteins, polynucleotide encoding such proteins or fragments thereof, and vectors comprising the polynucleotides encoding the innovative proteins. Exemplary bispecific molecules include antibody-like protein dimers based on the tenth fibronectin type III domain.


Find Patent Forward Citations

Loading…