The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 26, 2017
Filed:
Dec. 19, 2013
Applicant:
University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Inventors:
Kazunori Koide, Pittsburgh, PA (US);
Sami Saif Eldin Ali Osman, Pittsburgh, PA (US);
Assignee:
University of Pittsburgh—Of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 493/10 (2006.01); C07D 413/14 (2006.01); C07D 413/12 (2006.01); C07C 49/603 (2006.01); C07D 309/30 (2006.01); C07D 407/06 (2006.01); C07D 493/04 (2006.01);
U.S. Cl.
CPC ...
C07D 493/10 (2013.01); C07C 49/603 (2013.01); C07D 309/30 (2013.01); C07D 407/06 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 493/04 (2013.01);
Abstract
The present invention provides novel analogs of FR901464, as well as an improved methodology for preparing FR901464 and its analogs. These compounds display an anti-cancer activity and are candidates for therapies against a number of disease states associated with dysfunctional RNA splicing.