The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 26, 2017

Filed:

Jul. 08, 2014
Applicant:

Ono Pharmaceutical Co., Ltd., Osaka-shi, JP;

Inventors:

Masahiko Terakado, Osaka, JP;

Masaya Hirobe, Osaka, JP;

Maki Iwahashi, Osaka, JP;

Kousuke Tani, Osaka, JP;

Tetsuya Sugiyama, Ibaraki, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/14 (2006.01); C07D 417/04 (2006.01); A61K 31/454 (2006.01); A61K 31/4545 (2006.01); A61K 45/06 (2006.01); A61K 31/435 (2006.01);
U.S. Cl.
CPC ...
C07D 417/14 (2013.01); A61K 31/435 (2013.01); A61K 31/454 (2013.01); A61K 31/4545 (2013.01); A61K 45/06 (2013.01); C07D 417/04 (2013.01);
Abstract

The present invention provides a compound having ALXR agonist activity. Specifically, the invention provides a compound having ALXR agonist activity represented by general formula (I) wherein all the symbols are as defined in the specification, a salt thereof, a solvate thereof, or a prodrug thereof as well as an agent containing the same as an active ingredient for preventing and/or treating an ALXR-associated disease, such as an inflammatory bowel disease, an autoimmune disease, a chronic inflammatory disease, asthma, pulmonary fibrosis, atopic dermatitis, ischemia-reperfusion injury, myocardial infarction, or Alzheimer's disease.


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