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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9771345 B1

PDFFull Text
Date of Patent:
Sep. 26, 2017

Filed:

Oct. 07, 2010

Coferons and methods of making and using them

Applicants:

Francis Barany, New York, NY (US);

Maneesh Pingle, New York, NY (US);

Sarah Filippa Giardina, New York, NY (US);

Donald Bergstrom, West Lafayette, IN (US);

Lee Daniel Arnold, Mt. Sinai, NY (US);

Inventors:

Francis Barany, New York, NY (US);

Maneesh Pingle, New York, NY (US);

Sarah Filippa Giardina, New York, NY (US);

Donald Bergstrom, West Lafayette, IN (US);

Lee Daniel Arnold, Mt. Sinai, NY (US);

Assignees:

Cornell University, Ithaca, NY (US);

Purdue Research Foundation, West Lafayette, IN (US);

BlinkBio, Inc., New York, NY (US);

Attorney:

LeClair, a Professional Corporation

Primary Examiner:

Jason Sims

Assistant Examiner:

Ibrahim D Bori

Int. Cl.
CPC ...
A61K 31/69 (2006.01); C07D 319/14 (2006.01); C07D 207/12 (2006.01); C07D 207/24 (2006.01); C07D 209/52 (2006.01); C07D 239/42 (2006.01); C07D 239/54 (2006.01); C07D 241/36 (2006.01); C07D 263/20 (2006.01); C07D 295/18 (2006.01); C07D 307/80 (2006.01); C07D 317/10 (2006.01); C07D 317/44 (2006.01); C07D 319/12 (2006.01); C07D 403/06 (2006.01); C07D 403/14 (2006.01); C07D 405/14 (2006.01); C07D 413/06 (2006.01); C07D 471/14 (2006.01); C07D 491/04 (2006.01); C07D 491/10 (2006.01); C07D 491/14 (2006.01); C07F 5/02 (2006.01); C40B 30/04 (2006.01);
U.S. Cl.
CPC ...
C07D 319/14 (2013.01); C07D 207/12 (2013.01); C07D 207/24 (2013.01); C07D 209/52 (2013.01); C07D 239/42 (2013.01); C07D 239/54 (2013.01); C07D 241/36 (2013.01); C07D 263/20 (2013.01); C07D 295/18 (2013.01); C07D 307/80 (2013.01); C07D 317/10 (2013.01); C07D 317/44 (2013.01); C07D 319/12 (2013.01); C07D 403/06 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 413/06 (2013.01); C07D 471/14 (2013.01); C07D 491/04 (2013.01); C07D 491/10 (2013.01); C07D 491/14 (2013.01); C07F 5/025 (2013.01); C40B 30/04 (2013.01);
Abstract

The present invention is directed to a monomer useful in preparing therapeutic compounds. The monomer includes one or more pharmacophores which potentially binds to a target molecule with a dissociation constant of less than 300 μM and a linker element connected to the pharmacophore. The linker element has a molecular weight less than 500 daltons, is connected, directly or indirectly through a connector, to the pharmacophore.

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