The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 26, 2017

Filed:

Nov. 28, 2014
Applicant:

Universiteit Gent, Ghent, BE;

Inventors:

Johan Van Der Eycken, Ninove, BE;

Gert Smans, Rheinfelden, DE;

Jelle Cornelus, Zelzate, BE;

Dries Van Den Bossche, Ghent, BE;

Nick Jacobs, Ghent, BE;

Assignee:

UNIVERSITEIT GENT, Ghent, BE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 313/00 (2006.01); A61K 31/365 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 313/00 (2013.01); A61K 31/365 (2013.01); A61K 45/06 (2013.01);
Abstract

The present invention provides new therapeutic compounds for treatment of diseases caused or influenced by microtubule stability, such as proliferative diseases. The compounds are phenyl-analogs of the naturally occurring peloruside. The analogs are easier to synthesize, and hence open up the possibility to produce said compounds in large quantities for therapeutic use.


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