The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 26, 2017
Filed:
Nov. 30, 2012
Applicant:
Hangzhou Bensheng Pharmaceutical Co., Ltd., Zhejiang, CN;
Inventors:
Assignee:
HANGZHOU BENSHENG PHARMACEUTICAL CO., LTD., Hangzhou, Zhejiang, CN;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 307/87 (2006.01); C07J 75/00 (2006.01); C07J 73/00 (2006.01); A61K 31/56 (2006.01); C07D 307/77 (2006.01);
U.S. Cl.
CPC ...
C07D 307/87 (2013.01); A61K 31/56 (2013.01); C07D 307/77 (2013.01); C07J 73/003 (2013.01); C07J 75/00 (2013.01);
Abstract
The present invention belongs to the field of natural medicine and pharmaceutical chemistry, and specifically relates to novel 2-alkyl- or 2-aromatic-substituted tanshinone I derivatives of formula (I) or a pharmaceutically acceptable salt thereof, to a process for the preparation of these compounds, compositions containing such compounds and their use in preparing antineoplastic medicaments. When Z=R, said derivative is 2-alkyl-substituted tanshinone I; when Z=Ar, said derivative is 2-aryl-substituted tanshinone I; when Z=Het, said derivative is 2-heteroaryl- or 2-heterocyclyl-substituted tanshinone I.