The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 26, 2017
Filed:
May. 18, 2016
Applicant:
Cls Therapeutics Limited, Guernsey, Channel Islands, GB;
Inventors:
Dmitry Dmitrievich Genkin, Saint-Petersburg, RU;
Georgy Viktorovich Tets, Saint-Petersburg, RU;
Viktor Veniaminovich Tets, Saint-Petersburg, RU;
Assignee:
CLS Therapeutics Limited, Guernsey, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/46 (2006.01); C12Q 1/68 (2006.01); C12N 9/16 (2006.01); C12N 9/22 (2006.01);
U.S. Cl.
CPC ...
A61K 38/465 (2013.01); C12Q 1/6883 (2013.01); C12Y 301/00 (2013.01); C12Y 301/21001 (2013.01); C12Q 2600/156 (2013.01);
Abstract
The invention is directed to treatment of systemic DNA mutation diseases accompanied with development of somatic mosaicism and elevation of blood extracellular DNA. The inventive method comprises introducing a DNASE enzyme into the systemic blood circulation of a patient in doses and regimens which are sufficient to decrease average molecular weight of circulating extracellular blood DNA in the blood of said patient.