The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 26, 2017

Filed:

Sep. 05, 2013
Applicant:

Freie Universität Berlin, Berlin, DE;

Inventors:

Rainer Haag, Berlin, DE;

Dirk Steinhilber, Berlin, DE;

Wolfgang Friess, Iffeldorf, DE;

Sarah Küchler, München, DE;

Madeleine Witting, München, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 38/38 (2006.01); C07K 16/00 (2006.01); B01J 13/00 (2006.01); A61K 9/06 (2006.01); A61K 38/50 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5146 (2013.01); A61K 9/06 (2013.01); A61K 9/5192 (2013.01); A61K 38/385 (2013.01); A61K 38/50 (2013.01); B01J 13/0065 (2013.01); C07K 16/00 (2013.01); C12Y 302/01017 (2013.01); C12Y 305/01001 (2013.01);
Abstract

A method for producing a polyglycerol nanogel is disclosed, the method comprising the following steps: Mixing an aqueous solution of first polyglycerol macromonomers, which are modified with a first reactive group, with an aqueous solution of second polyglycerol macromonomers, which are modified with a second reactive group, wherein the first reactive group and the second reactive group can react with each other forming a chemical bond; transferring the mixture into an organic non-solvent; and precipitation of a polyglycerol nanogel consisting of first polyglycerol macromonomers and second polyglycerol macromonomers which are covalently bound to each other. According to an aspect of the invention, the method is characterized in that the organic non-solvent is miscible with water and in that the method is carried out without adding surface-active substances.


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