The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 26, 2017

Filed:

May. 24, 2007
Applicants:

Gary Owens, Earlysville, VA (US);

Whye-kei Lye, Charlottesville, VA (US);

Michael Reed, Charlottesville, VA (US);

Joshua Spradlin, Charlottesville, VA (US);

Brian Wamhoff, Charlottesville, VA (US);

Matthew Hudson, Charlottesville, VA (US);

Kareen Looi, Charlottesville, VA (US);

Inventors:

Gary Owens, Earlysville, VA (US);

Whye-Kei Lye, Charlottesville, VA (US);

Michael Reed, Charlottesville, VA (US);

Joshua Spradlin, Charlottesville, VA (US);

Brian Wamhoff, Charlottesville, VA (US);

Matthew Hudson, Charlottesville, VA (US);

Kareen Looi, Charlottesville, VA (US);

Assignee:

University of Virginia Patent Foundation, Charlottesville, VA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61F 2/82 (2013.01); A61F 2/91 (2013.01);
U.S. Cl.
CPC ...
A61F 2/91 (2013.01); A61F 2/82 (2013.01); A61F 2240/001 (2013.01); A61F 2250/0058 (2013.01);
Abstract

The present invention relates generally to medical devices containing nanoporous surfaces and methods for making same. More specifically, the invention relates to implantable vascular stents or other biomedical devices having at least one dealloyed nanoporous layer that promotes improved cellular adhesion properties that promote healing and long term biocompatibility. In the case of stents, the nanoporous layer promotes re-endothelialization at sites of stent implantation vasculature, improves overall healing, and reduces inflammation and intimal disease progression. The nanoporous layer may be optionally loaded with one or more therapeutic agent to further improve the function of the implanted stent and further augment clinical efficacy.


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