The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 19, 2017

Filed:

Oct. 17, 2013
Applicant:

Ahram Biosystems, Inc., Seoul, KR;

Inventors:

Hyun Jin Hwang, Seoul, KR;

Jeong Hee Kim, Seoul, KR;

Kyunghoon Jeong, Gwangju, KR;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/34 (2006.01); B01L 7/00 (2006.01);
U.S. Cl.
CPC ...
C12P 19/34 (2013.01); B01L 7/525 (2013.01); B01L 2300/1838 (2013.01); B01L 2300/1883 (2013.01); B01L 2400/0442 (2013.01); B01L 2400/0445 (2013.01);
Abstract

The present invention provides a nucleic acid sequence amplification method and apparatuses thereof that are simple in the design and easy to miniaturize and integrate into complex apparatuses, with capability of using DNA polymerases that are not thermostable. In the present invention, a plurality of heat sources are combined to supply or remove heat from specific regions of the sample such that a specific spatial temperature distribution is maintained inside the sample by locating a relatively high temperature region lower in height than a relatively low temperature region.


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