The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 19, 2017

Filed:

Jan. 20, 2015
Applicant:

Sanofi, Paris, FR;

Inventors:

Marine Bertin, Paris, FR;

Bruno Dumas, Paris, FR;

Assignee:

SANOFI, Paris, FR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/02 (2006.01); C12N 15/00 (2006.01); C12P 21/04 (2006.01); C12P 21/06 (2006.01); C12P 33/00 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
C12N 9/0079 (2013.01); C12N 9/0071 (2013.01); C12P 33/00 (2013.01);
Abstract

The present invention pertains to an isolated P450 enzyme comprising or consisting of an amino acid sequence at least 80% identical to SEQ ID NO: 1, wherein said sequence comprises a threonine at position corresponding to position 225 and/or an aspartic acid mutation at position corresponding to position 289. The invention also concerns an isolated nucleic acid comprising a sequence encoding said enzyme, a vector comprising said nucleic acid, and a host cell containing said nucleic acid or said vector. Methods for preparing said enzyme and methods for producing steroid hormone precursors using the enzyme or the host cells featured in the invention are also provided.


Find Patent Forward Citations

Bertin, Marine. (2017). Cytochrome p450 polypeptide with increased enzyme activity (U.S. Patent No. 9765307). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9765307

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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