The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 19, 2017

Filed:

Mar. 27, 2015
Applicants:

Snu R&db Foundation, Seoul, KR;

Institute for Basic Science, Daejeon, KR;

The Catholic University of Korea Industry-academic Cooperation Foundation, Seoul, KR;

Inventors:

Taeghwan Hyeon, Seoul, KR;

Kun Na, Gyeonggi-do, KR;

Daishun Ling, Seoul, KR;

Wooram Park, Gyeonggi-do, KR;

Byung Hyo Kim, Seoul, KR;

Hyeona Yim, Gyeonggi-do, KR;

Kyoung Sub Kim, Incheon, KR;

Michael J. Hackett, West Chester, OH (US);

Sin-jung Park, Seoul, KR;

Yang Lu, Hefei, KR;

Yong Sun Jeon, Incheon, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/06 (2006.01); C08G 69/08 (2006.01); C08G 69/40 (2006.01); C08G 81/00 (2006.01); A61K 49/18 (2006.01);
U.S. Cl.
CPC ...
C08G 69/40 (2013.01); A61K 49/1857 (2013.01); C08G 81/00 (2013.01); C08G 69/08 (2013.01);
Abstract

The present invention relates to MRI contrasting agent for contrasting cancer cell which contains ultrafine nanoparticles. More particularly, the present invention is directed to a self-assembled ligand composition comprising a ligand A, which is separated at a specific pH range, and a ligand B of which surface charge changes at a specific pH range, MRI contrast agent for contrasting cancer cell comprising said ligand composition and MRI contrasting nanoparticles, and the methods for preparing them.


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