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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9765107 B1

PDFFull Text
Date of Patent:
Sep. 19, 2017

Filed:

Jun. 16, 2014

Cyclic phosphonate substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases

Applicant:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Inventors:

Stephane Bogen, Somerset, NJ (US);

Vinay Girijavallabhan, Denville, NJ (US);

Quang Truong, Morganville, NJ (US);

Ping Chen, Edison, NJ (US);

Frank Bennett, Cranford, NJ (US);

Angela Kerekes, Plainfield, NJ (US);

Qun Dang, Westfield, NJ (US);

David B. Olsen, Lansdale, PA (US);

Ian Davies, Princeton, NJ (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:

Jeffrey P. Bergman

Catherine D. Fitch

Primary Examiner:

Patrick Lewis

Int. Cl.
CPC ...
A01N 43/04 (2006.01); A61K 31/70 (2006.01); C07H 19/10 (2006.01); A61K 45/06 (2006.01); A61K 31/661 (2006.01); C07F 9/6558 (2006.01); C07F 9/6574 (2006.01); C07H 19/11 (2006.01); A61K 31/7072 (2006.01); A61K 31/7068 (2006.01); A61K 31/706 (2006.01); A61K 31/7064 (2006.01);
U.S. Cl.
CPC ...
C07H 19/10 (2013.01); A61K 31/661 (2013.01); A61K 31/7072 (2013.01); A61K 45/06 (2013.01); C07F 9/65586 (2013.01); C07F 9/65744 (2013.01); C07H 19/11 (2013.01); A61K 31/706 (2013.01); A61K 31/7064 (2013.01); A61K 31/7068 (2013.01);
Abstract

The present invention relates to Cyclic Phosphonate Substituted Nucleoside Derivatives of Formula (I): (structure) and pharmaceutically acceptable salts thereof, wherein B, X, R1, R2 and R3 are as defined herein, as well as to compositions and methods of using the Cyclic Phosphonate Substituted Nucleoside Derivatives for treating or preventing HCV infection in a patient.

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