The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 19, 2017

Filed:

Sep. 06, 2011
Applicants:

Tetsuo Kiso, Tokyo, JP;

Mina Tsukamoto, Tokyo, JP;

Inventors:

Tetsuo Kiso, Tokyo, JP;

Mina Tsukamoto, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 249/08 (2006.01); C07D 403/04 (2006.01); A61K 31/4196 (2006.01); C07D 413/12 (2006.01);
U.S. Cl.
CPC ...
C07D 249/08 (2013.01); A61K 31/4196 (2013.01); C07D 403/04 (2013.01); C07D 413/12 (2013.01);
Abstract

[Problem] Provided is a pharmaceutical, in particular, a pharmaceutical composition which is useful for the treatment of pain. [Means for Solution] The present inventors have made extensive studies using model animals with pain for the purpose of providing a therapeutic agent for pain. As a result, they have found that 11β-hydroxydehydrogenase type 1 (11β-HSD1) inhibitor, in particular, a triazole compound having a cyclic group at the 3-position (or 5-position) of a triazole ring has a good effect of ameliorating chronic pain. That is, according to the present invention, a pharmaceutical composition comprising an 11β-HSD1 inhibitor, in particular, the triazole compound of the present invention, as an active ingredient, is useful for the treatment of pain (particularly, neuropathic pain or fibromyalgia).


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