The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 19, 2017

Filed:

Jun. 30, 2011
Applicants:

Lizbeth K. Hedstrom, Newton, MA (US);

Marcus Long, Somerville, MA (US);

Deviprasad R. Gollapalli, Waltham, MA (US);

Inventors:

Lizbeth K. Hedstrom, Newton, MA (US);

Marcus Long, Somerville, MA (US);

Deviprasad R. Gollapalli, Waltham, MA (US);

Assignee:

Brandeis University, Waltham, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/54 (2006.01); C07D 239/42 (2006.01); C07D 401/04 (2006.01); C07C 279/14 (2006.01); A61K 31/4184 (2006.01); A61K 31/505 (2006.01); C07C 65/40 (2006.01); C07C 211/12 (2006.01); C07D 239/49 (2006.01); C07D 271/12 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
C07C 279/14 (2013.01); A61K 31/4184 (2013.01); A61K 31/505 (2013.01); A61K 47/48023 (2013.01); A61K 47/48038 (2013.01); A61K 47/48061 (2013.01); C07C 65/40 (2013.01); C07C 211/12 (2013.01); C07D 239/49 (2013.01); C07D 271/12 (2013.01);
Abstract

Certain aspects of the invention relate to compounds, compositions and methods that are useful for treating or preventing a disease in a subject by enhancing the degradation of a protein. In other aspects, said compounds can be useful research tools for investigating protein degradation. In other aspects, said compounds are useful research tools for investigating protein function. In certain embodiments, the degraded protein is implicated in a disease or disorder whose pathology is related at least in part to the excessive expression of the protein or the expression of a mutant form of the protein.


Find Patent Forward Citations

Hedstrom, Lizbeth. (2017). Small-molecule-targeted protein degradation (U.S. Patent No. 9765019). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9765019

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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