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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9765017 B1

PDFFull Text
Expired
Date of Patent:
Sep. 19, 2017

Filed:

Dec. 22, 2014

Allosteric hemoglobin modifiers with nitric oxide releasing moiety

Applicant:

Virginia Commonwealth University, Richmond, VA (US);

Inventors:

Martin K. Safo, Richmond, VA (US);

Richmond Danso-Danquah, Richmond, VA (US);

Mohini Ghatge, Richmond, VA (US);

Jurgen Venitz, Richmond, VA (US);

Martin Mangino, Richmond, VA (US);

Kevin R. Ward, Richmond, VA (US);

Assignee:

VIRGINIA COMMONWEALTH UNIVERSITY, Richmond, VA (US);

Attorney:

Whitham, Curtis & Cook, P.C.

Primary Examiner:

Anna Pagonakis

Int. Cl.
CPC ...
C07C 235/38 (2006.01); A61K 31/655 (2006.01); C07C 245/24 (2006.01); A61K 31/216 (2006.01); A61K 31/40 (2006.01); A61K 33/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07C 235/38 (2013.01); A61K 31/216 (2013.01); A61K 31/40 (2013.01); A61K 31/655 (2013.01); A61K 33/00 (2013.01); A61K 45/06 (2013.01); C07C 245/24 (2013.01);
Abstract

Allosteric hemoglobin (Hb) modifiers of hemoglobin which contain nitric oxide (NO) moieties allowing for the release of NO in vivo. The compounds retain the oxygen delivery capability of the allosteric hemoglobin modifier to bind Hb and enhance Hb's ability to deliver oxygen to cells and tissues, and also release NO from the NO moiety. Methods of delivering oxygen and/or NO to cells and tissues are also provided.

Find Patent Forward Citations

Safo, Martin. (2017). Allosteric hemoglobin modifiers with nitric oxide releasing moiety (U.S. Patent No. 9765017). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9765017

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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