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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9764046 B1

PDFFull Text
Date of Patent:
Sep. 19, 2017

Filed:

Jan. 21, 2015

Labeling composition for intraocular tissue, labeling method of intraocular tissue, and screening method

Applicant:

Canon Kabushiki Kaisha, Tokyo, JP;

Inventors:

Kohei Watanabe, Yokohama, JP;

Taichi Shintou, Saitama, JP;

Tsuyoshi Nomoto, Tokyo, JP;

Takeshi Miyazaki, Yokohama, JP;

Toshio Tanaka, Tsu, JP;

Yuhei Nishimura, Tsu, JP;

Yasuhito Shimada, Tsu, JP;

Norihiro Nishimura, Tsu, JP;

Assignee:

CANON KABUSHIKI KAISHA, Tokyo, JP;

Attorney:

Fitzpatrick, Cella, Harper & Scinto

Primary Examiner:

Nissa Westerberg

Int. Cl.
CPC ...
A61K 49/00 (2006.01); C07D 221/18 (2006.01); C07D 235/02 (2006.01); C07D 277/08 (2006.01); C07D 277/62 (2006.01); C07D 263/54 (2006.01); C07D 209/70 (2006.01); C07D 209/96 (2006.01); C07D 215/00 (2006.01); C07D 221/14 (2006.01); C07D 277/34 (2006.01); C07D 277/36 (2006.01); C07D 277/64 (2006.01); C07D 311/82 (2006.01); C07D 311/86 (2006.01); C07D 405/04 (2006.01); C07D 405/06 (2006.01); C07D 413/04 (2006.01); C07D 413/06 (2006.01); C07D 417/04 (2006.01); C07D 417/06 (2006.01); C07D 417/14 (2006.01); C07D 491/052 (2006.01); C07D 491/12 (2006.01); C07D 497/10 (2006.01); G01N 33/50 (2006.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
A61K 49/0021 (2013.01); A61K 49/0002 (2013.01); A61K 49/006 (2013.01); A61K 49/0039 (2013.01); A61K 49/0041 (2013.01); C07D 209/70 (2013.01); C07D 209/96 (2013.01); C07D 215/00 (2013.01); C07D 221/14 (2013.01); C07D 221/18 (2013.01); C07D 263/54 (2013.01); C07D 277/34 (2013.01); C07D 277/36 (2013.01); C07D 277/64 (2013.01); C07D 311/82 (2013.01); C07D 311/86 (2013.01); C07D 405/04 (2013.01); C07D 405/06 (2013.01); C07D 413/04 (2013.01); C07D 413/06 (2013.01); C07D 417/04 (2013.01); C07D 417/06 (2013.01); C07D 417/14 (2013.01); C07D 491/052 (2013.01); C07D 491/12 (2013.01); C07D 497/10 (2013.01); G01N 33/5088 (2013.01); G01N 33/582 (2013.01); G01N 2333/4603 (2013.01);
Abstract

The invention provides a labeling composition for an intraocular tissue of a living individual, which specifically labels the intraocular tissue without need of an invasive operation such as exposure of an ocular tissue or injection of a staining agent into the ocular tissue or a nerve tissue linking to the ocular tissue, a method of noninvasively labeling an intraocular tissue of a living individual, and a screening method using the labeling composition for the intraocular tissues. The composition contains a compound capable of labeling at least a photoreceptor cell layer of a retina, wherein the compound is a staining compound having a particular structure as a partial structure thereof.

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