The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 19, 2017
Filed:
May. 02, 2012
Willow Diluzio, Westford, MA (US);
Nobel T. Truong, Milford, MA (US);
Csanad M. Varga, Cambridge, MA (US);
Vaithianathan Palaniappan, Andover, MA (US);
Jason Brown, Burlington, MA (US);
Catherine Scholz, Woburn, MA (US);
Willow Diluzio, Westford, MA (US);
Nobel T. Truong, Milford, MA (US);
Csanad M. Varga, Cambridge, MA (US);
Vaithianathan Palaniappan, Andover, MA (US);
Jason Brown, Burlington, MA (US);
Catherine Scholz, Woburn, MA (US);
Millennium Pharmaceuticals, Inc., Cambridge, MA (US);
Abstract
Antibody formulations are described comprising a mixture of a non-reducing sugar, an anti-α4β7 antibody and at least one amino acid. The disclosed formulations have improved stability, reduced aggregate formation, and may retard degradation of the anti-α4β7 antibody therein or exhibit any combinations thereof. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-α4β7 antibody in vivo.