The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 19, 2017

Filed:

Oct. 20, 2015
Applicant:

Auburn University, Auburn, AL (US);

Inventor:

Haroldo E. Toro, Auburn, AL (US);

Assignee:

Auburn University, Auburn, AL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/215 (2006.01); C12N 7/00 (2006.01); A61K 39/12 (2006.01); C07K 14/165 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/215 (2013.01); A61K 39/12 (2013.01); C07K 14/165 (2013.01); C12N 7/00 (2013.01); A61K 2039/5254 (2013.01); A61K 2039/545 (2013.01); A61K 2039/552 (2013.01); A61K 2039/57 (2013.01); C12N 2770/20034 (2013.01); C12N 2770/20064 (2013.01); C12N 2770/20071 (2013.01);
Abstract

Disclosed are methods for preparing a vaccine against infection by infectious bronchitis virus (IBV). The methods typically include passing a heterogeneous attenuated population of IBV in chicken embryonic kidney cells, and optionally may include further passaging the heterogeneous attenuated population of IBV in embryonated chicken eggs (ECE) in order to obtain passaged attenuated population of IBV. Also disclosed are passaged attenuated populations of IBV in which the populations display a desired degree of homogeneity. Also disclosed are vaccines comprising the passaged attenuated populations of IBV and methods of vaccination comprising administering the disclosed vaccines.


Find Patent Forward Citations

Loading…