The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 19, 2017
Filed:
Nov. 08, 2012
Applicant:
Cedars-sinai Medical Center, Los Angeles, CA (US);
Inventors:
Eduardo Marban, Santa Monica, CA (US);
Hee Cheol Cho, Los Angeles, CA (US);
Assignee:
Cedars-Sinai Medical Center, Los Angeles, CA (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61P 9/00 (2006.01); A61P 9/06 (2006.01); A61K 38/17 (2006.01); A61K 48/00 (2006.01); C12N 15/00 (2006.01); C07K 14/47 (2006.01); C12N 5/077 (2010.01); A61K 35/34 (2015.01);
U.S. Cl.
CPC ...
A61K 38/1709 (2013.01); A61K 35/34 (2013.01); C07K 14/4702 (2013.01); C12N 5/0657 (2013.01); A61K 48/00 (2013.01); C12N 2501/60 (2013.01); C12N 2506/02 (2013.01); C12N 2799/022 (2013.01);
Abstract
Several embodiments disclosed herein relate generally to methods and compositions for the generation of biological pacemakers. In some embodiments, the methods comprise contacting non-pacemaker cells with one or more transcription factors (in vivo or in vitro) and inducing pacemaker functionality in the cells.