The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 19, 2017

Filed:

Jul. 16, 2014
Applicant:

Novartis Ag, Basel, CH;

Inventors:

David Beattie, Horsham, GB;

Urs Baettig, Reinach, CH;

Darren Mark Legrand, Horsham, GB;

Andrew Stuart Lister, Broadbridge Heath, GB;

Jeffrey McKenna, Carlisle, MA (US);

David William Pearce, Horsham, GB;

David Andrew Sandham, Horsham, GB;

Oliver Ross Steward, Horsham, GB;

Christopher Thomson, Belmont, MA (US);

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/445 (2006.01); A61K 31/551 (2006.01); C07D 403/12 (2006.01); C07D 401/14 (2006.01); C07D 413/14 (2006.01); A61K 31/41 (2006.01); A61K 31/4245 (2006.01); A61K 31/427 (2006.01); A61K 31/5377 (2006.01); A61K 31/5513 (2006.01); C07D 401/10 (2006.01); C07D 401/12 (2006.01); C07D 403/10 (2006.01); C07D 403/14 (2006.01); C07D 407/12 (2006.01); C07D 413/10 (2006.01); C07D 413/12 (2006.01); C07D 417/10 (2006.01); C07D 417/14 (2006.01); C07D 257/04 (2006.01); A61K 45/06 (2006.01); A61K 31/45 (2006.01); A61K 31/496 (2006.01); A61K 31/504 (2006.01); A61K 31/439 (2006.01); A61K 31/454 (2006.01); A61K 31/4545 (2006.01); A61K 31/506 (2006.01); C07D 405/12 (2006.01); C07D 471/08 (2006.01);
U.S. Cl.
CPC ...
A61K 31/551 (2013.01); A61K 31/41 (2013.01); A61K 31/427 (2013.01); A61K 31/4245 (2013.01); A61K 31/439 (2013.01); A61K 31/445 (2013.01); A61K 31/45 (2013.01); A61K 31/454 (2013.01); A61K 31/4545 (2013.01); A61K 31/496 (2013.01); A61K 31/504 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); A61K 31/5513 (2013.01); A61K 45/06 (2013.01); C07D 257/04 (2013.01); C07D 401/10 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/10 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 405/12 (2013.01); C07D 407/12 (2013.01); C07D 413/10 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/10 (2013.01); C07D 417/14 (2013.01); C07D 471/08 (2013.01);
Abstract

The present invention relates to novel compounds that are autotaxin inhibitors, processes for their preparation, pharmaceutical compositions and medicaments containing them and to their use in diseases and disorders mediated by autotaxin.


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