The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 12, 2017
Filed:
Jul. 09, 2015
Applicant:
Scholar Rock, Inc., Cambridge, MA (US);
Inventors:
Thomas Schurpf, Cambridge, MA (US);
Nagesh K. Mahanthappa, Cambridge, MA (US);
Michelle Marie Straub, Brighton, MA (US);
Assignee:
Scholar Rock, Inc., Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/22 (2006.01); A61K 39/395 (2006.01); C07K 14/495 (2006.01); C07K 16/00 (2006.01); C07K 16/28 (2006.01); C12N 15/10 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); A61K 39/3955 (2013.01); C07K 14/495 (2013.01); C07K 16/005 (2013.01); C07K 16/2863 (2013.01); C12N 15/1037 (2013.01); A61K 38/00 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/55 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01); G01N 2333/71 (2013.01);
Abstract
Provided herein are antibodies that bind growth factor prodomain complexes, for example, growth factor prodomain complexes that include GDF-8 growth factor and GDF-8 prodomain. Also included are antibodies that bind growth factor prodomain complexes that have been altered by proteolytic processing.