The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 12, 2017
Filed:
Oct. 18, 2013
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Yale University, New Haven, CT (US);
Nathanael Gray, Boston, MA (US);
Ting Xie, Boston, MA (US);
Sang Min Lim, San Diego, CA (US);
Pasi A. Janne, Needham, MA (US);
Craig M. Crews, New Haven, CT (US);
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Yale University, New Haven, CT (US);
Abstract
Provided are bifunctional small molecules of Formula (I): or pharmaceutically acceptable salts thereof, wherein M represents a small organic molecule which binds, covalently or non-covalently, a kinase, such as Her3 protein kinase; Lrepresents a linker; and Rrepresents a hydrophobic group. An example of a compound of Formula (I) is a compound of Formula (II): Also provided are pharmaceutical compositions comprising a compound of Formula (I) or (II) and methods of using such compounds for treating proliferative diseases.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile