The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 12, 2017
Filed:
Sep. 21, 2016
Applicant:
Shionogi & Co., Ltd., Osaka, JP;
Inventors:
Ken-ichi Kusakabe, Osaka, JP;
Syuhei Yoshida, Osaka, JP;
Kenji Nakahara, Osaka, JP;
Tsuyoshi Hasegawa, Osaka, JP;
Genta Tadano, Osaka, JP;
Kouki Fuchino, Osaka, JP;
Assignee:
SHIONOGI & CO., LTD., Osaka, JP;
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/12 (2006.01); C07D 413/14 (2006.01); C07D 498/04 (2006.01); C07D 498/10 (2006.01); C07D 413/04 (2006.01);
U.S. Cl.
CPC ...
C07D 413/12 (2013.01); C07D 413/04 (2013.01); C07D 413/14 (2013.01); C07D 498/04 (2013.01); C07D 498/10 (2013.01);
Abstract
The present invention provides a compound which has an effect of inhibiting amyloid β production, especially an effect of inhibiting BACE1, and which is useful as a therapeutic or prophylactic agent for diseases induced by production, secretion and/or deposition of amyloid β proteins. A compound of the formula (I): wherein X is —C(R)(R)—, —C(R)(R)—C(R)(R)— or —C(R)═C(R)—, Ris substituted or unsubstituted alkyl or the like,