The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 12, 2017

Filed:

Jul. 18, 2013
Applicant:

Sumitomo Dainippon Pharma Co., Ltd., Osaka-shi, Osaka, JP;

Inventors:

Yohei Ikuma, Osaka, JP;

Nobuhisa Fukuda, Osaka, JP;

Masato Iwata, Osaka, JP;

Hidenori Kimura, Osaka, JP;

Kuniko Suzuki, Osaka, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 207/16 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 409/12 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 491/048 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
C07D 207/16 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 409/12 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 491/048 (2013.01);
Abstract

A compound represented by formula (1) (in the formula: ring-D represents a three- to eight-membered hydrocarbon ring; Rrepresents an optionally substituted amino Calkyl group or the like; Rand Reach independently represent a hydrogen atom, a halogen atom, or the like; Rrepresents an optionally substituted Caryl group or the like; Rrepresents a hydrogen atom or the like; and ring-Q represents a (hetero)aryl group or the like which may be substituted with a carboxyl group or the like) or a pharmaceutically acceptable salt thereof exhibits an excellent FXIa inhibitory activity, and is useful as a therapeutic agent against thrombosis or the like.


Find Patent Forward Citations

Loading…