The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 12, 2017

Filed:

Jul. 05, 2013
Applicants:

Consejo Nacional DE Investigaciones Cientificas Y Tecnicas (Conicet), Buenos Aires, AR;

Inserm (Institut National DE LA Sante ET DE LA Recherche Medicale), Paris, FR;

Universidad Catolica DE Cordoba, Cordoba, AR;

Assistance Publique Hopitaux DE Paris, Paris, FR;

Universite Pierre ET Marie Curie (Paris 6), Paris, FR;

Inventors:

David Klatzmann, Paris, FR;

Eliane Piaggio, Paris, FR;

Hugo Lujan, Cordoba, AR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/26 (2006.01); A61K 38/27 (2006.01); C07K 14/44 (2006.01); A61K 47/48 (2006.01); A61K 38/28 (2006.01); A61K 38/29 (2006.01); A61K 38/20 (2006.01); A61K 47/42 (2017.01);
U.S. Cl.
CPC ...
A61K 47/48246 (2013.01); A61K 38/2013 (2013.01); A61K 38/2066 (2013.01); A61K 38/26 (2013.01); A61K 38/27 (2013.01); A61K 38/28 (2013.01); A61K 38/29 (2013.01); A61K 47/42 (2013.01); C07K 14/44 (2013.01); C07K 2319/02 (2013.01); C07K 2319/21 (2013.01);
Abstract

The invention provides compositions for oral delivery and methods of treatment using VSP carriers, such assp. variable surface proteins (VSP), to deliver therapeutic agents. VSP drug carriers can be combined with bioactive peptides, e.g., insulin, glucagon, or hGH, and be administered orally or mucosally. VSP carriers are resistant to acidic pHs and to proteolytic degradation and protect therapeutic agents from degradation in the gastrointestinal tract.


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