The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 12, 2017

Filed:

May. 06, 2014
Applicant:

Dyax Corp., Cambridge, MA (US);

Inventors:

Henry Blair, Boston, MA (US);

Thomas Beck, Concord, MA (US);

Robert Charles Ladner, Ijamsville, MD (US);

Assignee:

Dyax Corp., Burlington, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/55 (2006.01); A61K 38/57 (2006.01); A61K 31/195 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 38/55 (2013.01); A61K 31/195 (2013.01); A61K 38/57 (2013.01); A61K 45/06 (2013.01);
Abstract

Methods, kits and compositions are described that include a non-naturally occurring kallikrein inhibitor and an anti-thrombolytic agent, e.g., an anti-fibrinolytic agent, for preventing or reducing blood loss and/or ischemia, e.g., ischemia associated with perioperative blood loss and cerebral ischemia, the onset of systemic inflammatory response, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia or a focal brain ischemia, e.g., in patients subjected to invasive surgical procedures, especially procedures requiring cardiopulmonary bypass.


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