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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9757334 B1

PDFFull Text
Date of Patent:
Sep. 12, 2017

Filed:

Jul. 02, 2015

Surfactant-stripped micelle compositions with high cargo to surfactant ratio

Applicant:

The Research Foundation for the State University of New York, Amherst, NY (US);

Inventors:

Jonathan Lovell, Niagara Falls, CA;

Yumiao Zhang, Buffalo, NY (US);

Wentao Song, Brooklyn, NY (US);

Jumin Geng, Buffalo, NY (US);

Chulhong Kim, Ponhang-si, KR;

Mansik Jeon, Pohang-si, KR;

Assignee:

The Research Foundation for The State University of New York, Buffalo, NY (US);

Attorney:

Hodgson Russ LLP

Primary Examiner:

Robert Cabral

Int. Cl.
CPC ...
A61K 9/107 (2006.01); A61K 47/34 (2017.01); A61K 31/122 (2006.01); A61K 49/00 (2006.01); A61K 38/13 (2006.01); A61K 31/343 (2006.01); A61K 31/7048 (2006.01); A61K 31/568 (2006.01); A61K 31/593 (2006.01); A61K 31/23 (2006.01); A61K 31/436 (2006.01); A61K 31/567 (2006.01); A61K 31/337 (2006.01); A61K 31/355 (2006.01); A61K 31/592 (2006.01); A61K 31/01 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1075 (2013.01); A61K 31/01 (2013.01); A61K 31/122 (2013.01); A61K 31/23 (2013.01); A61K 31/337 (2013.01); A61K 31/343 (2013.01); A61K 31/355 (2013.01); A61K 31/436 (2013.01); A61K 31/567 (2013.01); A61K 31/568 (2013.01); A61K 31/592 (2013.01); A61K 31/593 (2013.01); A61K 31/7048 (2013.01); A61K 38/13 (2013.01); A61K 47/34 (2013.01); A61K 49/0021 (2013.01); A61K 49/0032 (2013.01); A61K 49/0041 (2013.01);
Abstract

Provided are compositions and methods relating to hydrophobic agent loaded-micelle. The micelles comprise surfactant (such as poloxamer) and have hydrophobic agents incorporated therein. The compositions substantially lack surfactant that is not associated with the micelles. The compositions are able to achieve high hydrophobic agent: surfactant molar ratio. The compositions can be used for drug delivery and imaging applications.

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