The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 05, 2017
Filed:
May. 03, 2013
Applicant:
The Johns Hopkins University, Baltimore, MD (US);
Inventors:
Alexandru V. Olaru, Towson, MD (US);
Stephen J. Meltzer, Lutherville, MD (US);
Assignee:
The Johns Hopkins University, Baltimore, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); G01N 33/574 (2006.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6883 (2013.01); C12N 15/111 (2013.01); C12Q 1/6886 (2013.01); G01N 33/57419 (2013.01); C12N 2310/141 (2013.01); C12N 2320/10 (2013.01); C12Q 2600/16 (2013.01); C12Q 2600/178 (2013.01); G01N 2800/065 (2013.01);
Abstract
The present invention relates to the field of biomarkers. More specifically, the present invention relates to the use of microRNAs to diagnose and monitor various diseases such as cancer. In particular embodiments, microRNA expression levels can serve as diagnostic biomarkers in inflammatory bowel disease-associated neoplasia (IBDN). More specifically, in certain embodiments, the present invention can be used to differentiate or distinguish IBDN from sporadic colorectal cancer (S-CRC), IBD-Dysplasia, IBD and/or normal.