The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 05, 2017

Filed:

Mar. 14, 2013
Applicant:

Reference Biolabs Inc., Seoul, KR;

Inventors:

Young Kee Shin, Seoul, KR;

Young-Deug Kim, Incheon, KR;

Jun Young Choi, Gwangmyeong-si, KR;

Myung Seok Lee, Seoul, KR;

Assignee:

Abion Inc., Seoul, KR;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 5/00 (2006.01); C07K 5/12 (2006.01); C07K 7/04 (2006.01); C07K 14/00 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07K 16/28 (2013.01); C07K 2317/24 (2013.01); C07K 2317/34 (2013.01); C07K 2317/622 (2013.01);
Abstract

A multi-transmembrane protein antigen includes a polypeptide corresponding to an extracellular loop of the multi-transmembrane protein, the N-terminal and C-terminal of the polypeptide being fixed on a solid substrate or the N-terminal and C-terminal being attached to both ends of a linker to form a cyclic structure, an antibody specifically binding to the antigen or an antigen-binding fragment thereof, and a method for screening an antibody specifically binding to the antigen. The present invention may be usefully employed for effective production of antibodies for multi-transmembrane proteins that play important roles in disease-related phenomena such as cell signaling.


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