The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 05, 2017
Filed:
Oct. 26, 2012
Applicants:
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Washington, DC (US);
Federal Budgetary Research Institution State Research Center of Virology and Biotechnology “vector”, Novosibirsk, RU;
Inventors:
Marian Elaine Major, Alexandria, VA (US);
Alla Kachko, Silver Spring, MD (US);
Galina Vadimovna Kochneva, Novosibirsk, RU;
Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/10 (2006.01); A61K 39/29 (2006.01); A61K 45/06 (2006.01); C07K 14/005 (2006.01); C12N 7/00 (2006.01); G01N 33/576 (2006.01); C12Q 1/04 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/109 (2013.01); A61K 39/29 (2013.01); A61K 45/06 (2013.01); C07K 14/005 (2013.01); C12N 7/00 (2013.01); G01N 33/5767 (2013.01); A61K 2039/5256 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C12N 2770/24222 (2013.01); C12N 2770/24234 (2013.01); C12Q 1/04 (2013.01);
Abstract
Novel epitope regions on hepatitis C virus E1E2 glycoprotein that induce a neutralizing antibody response in vivo are identified. Cross-neutralizing monoclonal antibodies that bind specifically to the epitopes are disclosed.