The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 05, 2017

Filed:

Nov. 01, 2013
Applicants:

University of Washington Through Its Center for Commercialization, Seattle, WA (US);

Children's Hospital Medical Center, Cincinnati, OH (US);

Inventors:

Jeremy Duffield, Seattle, WA (US);

Shuyu Ren, Shoreline, WA (US);

Rashmi Hedge, Cincinnati, OH (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 8/64 (2006.01); A61K 38/17 (2006.01); C07K 14/435 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4703 (2013.01); A61K 38/1709 (2013.01);
Abstract

The present disclosure provides molecules, compositions and methods for treating scarring in organs. The molecules, compositions and methods treat scarring by modulating the WNT, platelet-derived growth factor receptor (PDGFR), transforming growth factor-beta (TGF3) and/or connective-tissue growth factor (CTGF) signaling pathways.


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